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Gene Density, Transcription and Insulators Contribute to the Partition of the Drosophila Genome into Physical Domains
The mechanisms responsible for the establishment of physical domains in metazoan chromosomes are poorly understood. Here we find that physical domains in Drosophila chromosomes are demarcated at regions of active transcription and high gene density that are enriched for transcription factors and spe...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496039/ https://ncbi.nlm.nih.gov/pubmed/23041285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.031 |
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