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Insulators and imprinting from flies to mammals

The nuclear factor CTCF has been shown to be necessary for the maintenance of genetic imprinting at the mammalian H19/Igf2 locus. MacDonald and colleagues now report in BMC Biology that the mechanisms responsible for maintaining the imprinted state in Drosophila may be evolutionarily conserved and t...

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Détails bibliographiques
Auteurs principaux: Hou, Chunhui, Corces, Victor G
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912829/
https://ncbi.nlm.nih.gov/pubmed/20687908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-8-104
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