Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves

The calcification process in aortic stenosis has garnered considerable interest but only limited investigation into selected signaling pathways. This study investigated mechanisms related to hypoxia, hyaluronan homeostasis, brown adipocytic differentiation, and ossification within calcified valves....

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Main Authors: Stephens, Elizabeth H., Saltarrelli, Jerome G., Balaoing, Liezl R., Baggett, L. Scott, Nandi, Indrajit, Anderson, Kristin M., Morrisett, Joel D., Reardon, Michael J., Simpson, Melanie A., Weigel, Paul H., Olmsted-Davis, Elizabeth A., Davis, Alan R., Grande-Allen, K. Jane
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496006/
https://ncbi.nlm.nih.gov/pubmed/23017666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prp.2012.08.001
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