Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves

The calcification process in aortic stenosis has garnered considerable interest but only limited investigation into selected signaling pathways. This study investigated mechanisms related to hypoxia, hyaluronan homeostasis, brown adipocytic differentiation, and ossification within calcified valves....

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Hoofdauteurs: Stephens, Elizabeth H., Saltarrelli, Jerome G., Balaoing, Liezl R., Baggett, L. Scott, Nandi, Indrajit, Anderson, Kristin M., Morrisett, Joel D., Reardon, Michael J., Simpson, Melanie A., Weigel, Paul H., Olmsted-Davis, Elizabeth A., Davis, Alan R., Grande-Allen, K. Jane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496006/
https://ncbi.nlm.nih.gov/pubmed/23017666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prp.2012.08.001
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