Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves

The calcification process in aortic stenosis has garnered considerable interest but only limited investigation into selected signaling pathways. This study investigated mechanisms related to hypoxia, hyaluronan homeostasis, brown adipocytic differentiation, and ossification within calcified valves....

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Detalhes bibliográficos
Main Authors: Stephens, Elizabeth H., Saltarrelli, Jerome G., Balaoing, Liezl R., Baggett, L. Scott, Nandi, Indrajit, Anderson, Kristin M., Morrisett, Joel D., Reardon, Michael J., Simpson, Melanie A., Weigel, Paul H., Olmsted-Davis, Elizabeth A., Davis, Alan R., Grande-Allen, K. Jane
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496006/
https://ncbi.nlm.nih.gov/pubmed/23017666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prp.2012.08.001
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