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Independence of the positive inotropic effect of ouabain from the inhibition of the heart Na+/K+ pump.

Isolated left atria from guinea pigs were stimulated at 3.3 Hz and bathed at 30 degrees C in Tyrode's solution containing 6 mM KCl. After equilibration, this solution was replaced by a low-K solution or by Tyrode's solution containing ouabain or dihydroouabain. These treatments evoked an i...

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Bibliographic Details
Main Authors: Godfraind, T, Ghysel-Burton, J
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC349548/
https://ncbi.nlm.nih.gov/pubmed/6248887
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