Independence of the positive inotropic effect of ouabain from the inhibition of the heart Na+/K+ pump.
Isolated left atria from guinea pigs were stimulated at 3.3 Hz and bathed at 30 degrees C in Tyrode's solution containing 6 mM KCl. After equilibration, this solution was replaced by a low-K solution or by Tyrode's solution containing ouabain or dihydroouabain. These treatments evoked an increase in...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1980
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6248887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.3067 |
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