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Independence of the positive inotropic effect of ouabain from the inhibition of the heart Na+/K+ pump.

Isolated left atria from guinea pigs were stimulated at 3.3 Hz and bathed at 30 degrees C in Tyrode's solution containing 6 mM KCl. After equilibration, this solution was replaced by a low-K solution or by Tyrode's solution containing ouabain or dihydroouabain. These treatments evoked an increase in...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Godfraind, T, Ghysel-Burton, J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1980
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349548/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6248887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.3067
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