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Chemoenzymatic Reversible Immobilization and Labeling of Proteins without Prior Purification

Site-specific chemical modification of proteins is important for many applications in biology and biotechnology. Recently, our laboratory and others have exploited the high specificity of the enzyme protein farnesyltransferase (PFTase) to site-specifically modify proteins through the use of alternat...

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Main Authors: Rashidian, Mohammad, Song, James M., Pricer, Rachel E., Distefano, Mark D.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495177/
https://ncbi.nlm.nih.gov/pubmed/22435540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211308s
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