Neuroprotective Effects of Sulforaphane after Contusive Spinal Cord Injury

Traumatic spinal cord injury (SCI) leads to oxidative stress, calcium mobilization, glutamate toxicity, the release of proinflammatory factors, and depletion of reduced glutathione (GSH) at the site of injury. Induction of the Keap1/Nrf2/ARE pathway can alleviate neurotoxicity by protecting against...

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Detalhes bibliográficos
Main Authors: Benedict, Andrea L., Mountney, Andrea, Hurtado, Andres, Bryan, Kelley E., Schnaar, Ronald L., Dinkova-Kostova, Albena T., Talalay, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495118/
https://ncbi.nlm.nih.gov/pubmed/22853439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2012.2474
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