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Sialidase enhances recovery from spinal cord contusion injury

Axons fail to regenerate in the injured spinal cord, limiting motor and autonomic recovery and contributing to long-term morbidity. Endogenous inhibitors, including those on residual myelin, contribute to regeneration failure. One inhibitor, myelin-associated glycoprotein (MAG), binds to sialoglycan...

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Main Authors: Mountney, Andrea, Zahner, Matthew R., Lorenzini, Ileana, Oudega, Martin, Schramm, Lawrence P., Schnaar, Ronald L.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895144/
https://ncbi.nlm.nih.gov/pubmed/20534525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006683107
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