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Sialidase enhances spinal axon outgrowth in vivo

The adult CNS is an inhibitory environment for axon outgrowth, severely limiting recovery from traumatic injury. This limitation is due, in part, to endogenous axon regeneration inhibitors (ARIs) that accumulate at CNS injury sites. ARIs include myelin-associated glycoprotein, Nogo, oligodendrocyte-...

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Detalhes bibliográficos
Main Authors: Yang, Lynda J. S., Lorenzini, Ileana, Vajn, Katarina, Mountney, Andrea, Schramm, Lawrence P., Schnaar, Ronald L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544173/
https://ncbi.nlm.nih.gov/pubmed/16847268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604613103
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