Quantitative global and gene-specific promoter methylation in relation to biological properties of neuroblastomas

BACKGROUND: In this study we aimed to quantify tumor suppressor gene (TSG) promoter methylation densities levels in primary neuroblastoma tumors and cell lines. A subset of these TSGs is associated with a CpG island methylator phenotype (CIMP) in other tumor types. METHODS: The study panel consisted...

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Main Authors: Kiss, Nimrod B, Kogner, Per, Johnsen, John Inge, Martinsson, Tommy, Larsson, Catharina, Geli, Janos
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495052/
https://ncbi.nlm.nih.gov/pubmed/22984959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-83
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