Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

β-Defensins are cationic host defense peptides that form an amphipathic structure stabilized by three intramolecular disulfide bonds. They are key players in innate and adaptive immunity and have recently been shown to limit the production of pro-inflammatory cytokines in TLR4-stimulated macrophages...

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Detalhes bibliográficos
Main Authors: Semple, Fiona, MacPherson, Heather, Webb, Sheila, Cox, Sarah L, Mallin, Lucy J, Tyrrell, Christine, Grimes, Graeme R, Semple, Colin A, Nix, Matthew A, Millhauser, Glenn L, Dorin, Julia R
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2011
Assuntos:
Immunomodulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494976/
https://ncbi.nlm.nih.gov/pubmed/21809339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141648
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