Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

β-Defensins are cationic host defense peptides that form an amphipathic structure stabilized by three intramolecular disulfide bonds. They are key players in innate and adaptive immunity and have recently been shown to limit the production of pro-inflammatory cytokines in TLR4-stimulated macrophages...

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Bibliographische Detailangaben
Hauptverfasser: Semple, Fiona, MacPherson, Heather, Webb, Sheila, Cox, Sarah L, Mallin, Lucy J, Tyrrell, Christine, Grimes, Graeme R, Semple, Colin A, Nix, Matthew A, Millhauser, Glenn L, Dorin, Julia R
Format: Artigo
Sprache:Inglês
Veröffentlicht: WILEY-VCH Verlag 2011
Schlagworte:
Immunomodulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494976/
https://ncbi.nlm.nih.gov/pubmed/21809339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141648
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