Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

β-Defensins are cationic host defense peptides that form an amphipathic structure stabilized by three intramolecular disulfide bonds. They are key players in innate and adaptive immunity and have recently been shown to limit the production of pro-inflammatory cytokines in TLR4-stimulated macrophages...

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Dettagli Bibliografici
Autori principali: Semple, Fiona, MacPherson, Heather, Webb, Sheila, Cox, Sarah L, Mallin, Lucy J, Tyrrell, Christine, Grimes, Graeme R, Semple, Colin A, Nix, Matthew A, Millhauser, Glenn L, Dorin, Julia R
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY-VCH Verlag 2011
Soggetti:
Immunomodulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494976/
https://ncbi.nlm.nih.gov/pubmed/21809339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141648
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