Conformation of receptor-bound visual arrestin

Arrestin-1 (visual arrestin) binds to light-activated phosphorylated rhodopsin (P-Rh*) to terminate G-protein signaling. To map conformational changes upon binding to the receptor, pairs of spin labels were introduced in arrestin-1 and double electron–electron resonance was used to monitor interspin...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Miyeon, Vishnivetskiy, Sergey A., Van Eps, Ned, Alexander, Nathan S., Cleghorn, Whitney M., Zhan, Xuanzhi, Hanson, Susan M., Morizumi, Takefumi, Ernst, Oliver P., Meiler, Jens, Gurevich, Vsevolod V., Hubbell, Wayne L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494953/
https://ncbi.nlm.nih.gov/pubmed/23091036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216304109
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