miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours

Deregulated proliferation is a hallmark of cancer cells. Here, we show that microRNA-10b* is a master regulator of breast cancer cell proliferation and is downregulated in tumoural samples versus matched peritumoural counterparts. Two canonical CpG islands (5 kb) upstream from the precursor sequence...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Biagioni, Francesca, Bossel Ben-Moshe, Noa, Fontemaggi, Giulia, Canu, Valeria, Mori, Federica, Antoniani, Barbara, Di Benedetto, Anna, Santoro, Raffaela, Germoni, Sabrina, De Angelis, Fernanda, Cambria, Anna, Avraham, Roi, Grasso, Giuseppe, Strano, Sabrina, Muti, Paola, Mottolese, Marcella, Yarden, Yosef, Domany, Eytan, Blandino, Giovanni
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: WILEY-VCH Verlag 2012
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494877/
https://ncbi.nlm.nih.gov/pubmed/23125021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201483
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