miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours

Deregulated proliferation is a hallmark of cancer cells. Here, we show that microRNA-10b* is a master regulator of breast cancer cell proliferation and is downregulated in tumoural samples versus matched peritumoural counterparts. Two canonical CpG islands (5 kb) upstream from the precursor sequence...

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Detalhes bibliográficos
Main Authors: Biagioni, Francesca, Bossel Ben-Moshe, Noa, Fontemaggi, Giulia, Canu, Valeria, Mori, Federica, Antoniani, Barbara, Di Benedetto, Anna, Santoro, Raffaela, Germoni, Sabrina, De Angelis, Fernanda, Cambria, Anna, Avraham, Roi, Grasso, Giuseppe, Strano, Sabrina, Muti, Paola, Mottolese, Marcella, Yarden, Yosef, Domany, Eytan, Blandino, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494877/
https://ncbi.nlm.nih.gov/pubmed/23125021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201483
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