Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes

Transcription hinders replication fork progression and stability. The ATR checkpoint and specialized DNA helicases assist DNA synthesis across transcription units to protect genome integrity. Combining genomic and genetic approaches together with the analysis of replication intermediates, we searche...

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Main Authors: Alzu, Amaya, Bermejo, Rodrigo, Begnis, Martina, Lucca, Chiara, Piccini, Daniele, Carotenuto, Walter, Saponaro, Marco, Brambati, Alessandra, Cocito, Andrea, Foiani, Marco, Liberi, Giordano
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494831/
https://ncbi.nlm.nih.gov/pubmed/23141540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.041
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