Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes

Transcription hinders replication fork progression and stability. The ATR checkpoint and specialized DNA helicases assist DNA synthesis across transcription units to protect genome integrity. Combining genomic and genetic approaches together with the analysis of replication intermediates, we searche...

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Bibliografiske detaljer
Main Authors: Alzu, Amaya, Bermejo, Rodrigo, Begnis, Martina, Lucca, Chiara, Piccini, Daniele, Carotenuto, Walter, Saponaro, Marco, Brambati, Alessandra, Cocito, Andrea, Foiani, Marco, Liberi, Giordano
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494831/
https://ncbi.nlm.nih.gov/pubmed/23141540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.041
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