Antagonism of the neuropeptide S receptor with RTI-118 decreases cocaine self-administration and cocaine-seeking behavior in rats

Neuropeptide S (NPS) is a neuromodulatory peptide, acting via a G-protein-coupled receptor to regulate sleep, anxiety and behavioral arousal. Recent research has found that intracerebroventricular NPS can increase cocaine and alcohol self-administration in rodents, suggesting a key role in reward-re...

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Main Authors: Schmoutz, Christopher D, Zhang, Yanan, Runyon, Scott P, Goeders, Nicholas E
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494782/
https://ncbi.nlm.nih.gov/pubmed/22982682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2012.09.003
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