Effects of the neuropeptide S receptor antagonist RTI-118 on abuse-related facilitation of intracranial self-stimulation produced by cocaine and methylenedioxypyrovalerone (MDPV) in rats

Neuropeptide S (NPS) is a neurotransmitter that activates the NPS receptor to modulate biological functions including anxiety-like behaviors, feeding, and drug reinforcement. RTI-118 is a novel NPS receptor antagonist that decreased cocaine self-administration in rats at doses that had little or no...

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Veröffentlicht in:Eur J Pharmacol
Hauptverfasser: Bonano, Julie S., Runyon, Scott P., Hassler, Carla, Glennon, Richard A., Negus, S. Stevens
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259821/
https://ncbi.nlm.nih.gov/pubmed/25220242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.09.006
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