Modeling the Role of Negative Cooperativity in Metabolic Regulation and Homeostasis

A significant proportion of enzymes display cooperativity in binding ligand molecules, and such effects have an important impact on metabolic regulation. This is easiest to understand in the case of positive cooperativity. Sharp responses to changes in metabolite concentrations can allow organisms t...

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Dettagli Bibliografici
Autori principali: Bush, Eliot C., Clark, Anne E., DeBoever, Chris M., Haynes, Lillian E., Hussain, Sidra, Ma, Singer, McDermott, Matthew M., Novak, Adam M., Wentworth, John S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494708/
https://ncbi.nlm.nih.gov/pubmed/23152821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048920
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