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Modeling the Role of Negative Cooperativity in Metabolic Regulation and Homeostasis

A significant proportion of enzymes display cooperativity in binding ligand molecules, and such effects have an important impact on metabolic regulation. This is easiest to understand in the case of positive cooperativity. Sharp responses to changes in metabolite concentrations can allow organisms t...

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Hlavní autoři: Bush, Eliot C., Clark, Anne E., DeBoever, Chris M., Haynes, Lillian E., Hussain, Sidra, Ma, Singer, McDermott, Matthew M., Novak, Adam M., Wentworth, John S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494708/
https://ncbi.nlm.nih.gov/pubmed/23152821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048920
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