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Friend or foe: A novel role of β-defensins in tumor development

For many years, β-defensins were best known for their antimicrobial activity. However, β-defensins also exert immunomodulatory functions, such as the chemotactic recruitment of immune cells via chemokine receptors. We demonstrated that mouse β-defensin 14 recruits CCR6(+) B cells into fibrosarcomas,...

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Hlavní autoři: Röhrl, Johann, Geissler, Edward K., Hehlgans, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494629/
https://ncbi.nlm.nih.gov/pubmed/23170263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20825
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