Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication

RNA viruses can rapidly mutate and acquire resistance to drugs that directly target viral enzymes, which poses serious problems in a clinical context. Therefore, there is a growing interest in the development of antiviral drugs that target host factors critical for viral replication, since they are...

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Bibliografski detalji
Glavni autori: van der Schaar, Hilde M, van der Linden, Lonneke, Lanke, Kjerstin H W, Strating, Jeroen R P M, Pürstinger, Gerhard, de Vries, Erik, de Haan, Cornelis A M, Neyts, Johan, van Kuppeveld, Frank J M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494396/
https://ncbi.nlm.nih.gov/pubmed/22945356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.129
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