Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication

RNA viruses can rapidly mutate and acquire resistance to drugs that directly target viral enzymes, which poses serious problems in a clinical context. Therefore, there is a growing interest in the development of antiviral drugs that target host factors critical for viral replication, since they are...

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Bibliografiska uppgifter
Huvudupphovsmän: van der Schaar, Hilde M, van der Linden, Lonneke, Lanke, Kjerstin H W, Strating, Jeroen R P M, Pürstinger, Gerhard, de Vries, Erik, de Haan, Cornelis A M, Neyts, Johan, van Kuppeveld, Frank J M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2012
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494396/
https://ncbi.nlm.nih.gov/pubmed/22945356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.129
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