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Splicing Up Mdm2 for Cancer Proteome Diversity
Cancer cells often have high expression of Mdm2. However, in many cancers mdm2 is alternatively spliced, with more than 40 mRNA variants identified. Many of the alternative spliced mdm2 mRNAs have the potential to encode truncated Mdm2 isoforms. These putative Mdm2 isoforms can theoretically increas...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
SAGE Publications
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494376/ https://ncbi.nlm.nih.gov/pubmed/23150764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912455323 |
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