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Mdm2 and MdmX as Regulators of Gene Expression

p53 is an important tumor suppressor, functioning as a transcriptional activator and repressor. Upon receiving signals from multiple stress related pathways, p53 regulates numerous activities such as cell cycle arrest, senescence, and cell death. When p53 activities are not required, the protein is...

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書目詳細資料
Main Authors: Biderman, Lynn, Manley, James L., Prives, Carol
格式: Artigo
語言:Inglês
出版: SAGE Publications 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494367/
https://ncbi.nlm.nih.gov/pubmed/23150759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912455331
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