Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.
We have studied the binding of guanyl nucleotides to retinal rod outer segment membranes to determine how light activates a cyclic GMP phosphodiesterase and a GTPase. We found that rod outer segment membranes contain tightly bound radioactive GDP after incubation in the dark with [3H]GDP or [alpha-3...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6930647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2500 |
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