Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.
We have studied the binding of guanyl nucleotides to retinal rod outer segment membranes to determine how light activates a cyclic GMP phosphodiesterase and a GTPase. We found that rod outer segment membranes contain tightly bound radioactive GDP after incubation in the dark with [3H]GDP or [alpha-3...
Kaydedildi:
| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1980
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6930647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2500 |
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