Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.
We have studied the binding of guanyl nucleotides to retinal rod outer segment membranes to determine how light activates a cyclic GMP phosphodiesterase and a GTPase. We found that rod outer segment membranes contain tightly bound radioactive GDP after incubation in the dark with [3H]GDP or [alpha-3...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1980
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6930647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2500 |
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