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C2 domain membrane penetration by group IVA cytosolic phospholipase A(2) induces membrane curvature changes

Group IVA cytosolic phospholipase A(2) (cPLA(2)α) is an 85 kDa enzyme that regulates the release of arachidonic acid (AA) from the sn-2 position of membrane phospholipids. It is well established that cPLA(2)α binds zwitterionic lipids such as phosphatidylcholine in a Ca(2+)-dependent manner through...

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書誌詳細
主要な著者: Ward, Katherine E., Ropa, James P., Adu-Gyamfi, Emmanuel, Stahelin, Robert V.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494261/
https://ncbi.nlm.nih.gov/pubmed/22991194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M030718
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