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C2 domain membrane penetration by group IVA cytosolic phospholipase A(2) induces membrane curvature changes
Group IVA cytosolic phospholipase A(2) (cPLA(2)α) is an 85 kDa enzyme that regulates the release of arachidonic acid (AA) from the sn-2 position of membrane phospholipids. It is well established that cPLA(2)α binds zwitterionic lipids such as phosphatidylcholine in a Ca(2+)-dependent manner through...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494261/ https://ncbi.nlm.nih.gov/pubmed/22991194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M030718 |
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