AMP-activated protein kinase: an emerging drug target to regulate imbalances in lipid and carbohydrate metabolism to treat cardio-metabolic diseases: Thematic Review Series: New Lipid and Lipoprotein Targets for the Treatment of Cardiometabolic Diseases

The adenosine monophosphate-activated protein kinase (AMPK) is a metabolic sensor of energy metabolism at the cellular as well as whole-body level. It is activated by low energy status that triggers a switch from ATP-consuming anabolic pathways to ATP-producing catabolic pathways. AMPK is involved i...

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Главные авторы: Srivastava, Rai Ajit K., Pinkosky, Stephen L., Filippov, Sergey, Hanselman, Jeffrey C., Cramer, Clay T., Newton, Roger S.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2012
Предметы:
Thematic Review Section: New Lipid and Lipoprotein Targets for the Treatment of Cardiometabolic Diseases
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494254/
https://ncbi.nlm.nih.gov/pubmed/22798688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R025882
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