The PCSK9 decade: Thematic Review Series: New Lipid and Lipoprotein Targets for the Treatment of Cardiometabolic Diseases

PCSK9 proprotein convertase subtilisin/kexin type (PCSK9) is a crucial protein in LDL cholesterol (LDL-C) metabolism by virtue of its pivotal role in the degradation of the LDL receptor. In recent years, both in vitro and in vivo studies have greatly supplemented our understanding of the (patho)phys...

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Bibliographic Details
Main Authors: Lambert, Gilles, Sjouke, Barbara, Choque, Benjamin, Kastelein, John J. P., Hovingh, G. Kees
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2012
Subjects:
Thematic Review Section: New Lipid and Lipoprotein Targets for the Treatment of Cardiometabolic Diseases
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494258/
https://ncbi.nlm.nih.gov/pubmed/22811413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R026658
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