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Native Tandem and Ion Mobility Mass Spectrometry Highlight Structural and Modular Similarities in Clustered-Regularly-Interspaced Shot-Palindromic-Repeats (CRISPR)-associated Protein Complexes From Escherichia coli and Pseudomonas aeruginosa

The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated genes) immune system of bacteria and archaea provides acquired resistance against viruses and plasmids, by a strategy analogous to RNA-interference. Key components of the defense system are ribonucleoprotein...

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Detalhes bibliográficos
Main Authors: van Duijn, Esther, Barbu, Ioana M., Barendregt, Arjan, Jore, Matthijs M., Wiedenheft, Blake, Lundgren, Magnus, Westra, Edze R., Brouns, Stan J. J., Doudna, Jennifer A., van der Oost, John, Heck, Albert J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494201/
https://ncbi.nlm.nih.gov/pubmed/22918228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.020263
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