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Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer

A major goal in aging research is to improve health during aging. In the case of mice, genetic manipulations that shorten or lengthen telomeres result, respectively, in decreased or increased longevity. Based on this, we have tested the effects of a telomerase gene therapy in adult (1 year of age) a...

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Hlavní autoři: Bernardes de Jesus, Bruno, Vera, Elsa, Schneeberger, Kerstin, Tejera, Agueda M, Ayuso, Eduard, Bosch, Fatima, Blasco, Maria A
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY-VCH Verlag 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494070/
https://ncbi.nlm.nih.gov/pubmed/22585399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200245
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