Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer

A major goal in aging research is to improve health during aging. In the case of mice, genetic manipulations that shorten or lengthen telomeres result, respectively, in decreased or increased longevity. Based on this, we have tested the effects of a telomerase gene therapy in adult (1 year of age) a...

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Bibliographic Details
Main Authors: Bernardes de Jesus, Bruno, Vera, Elsa, Schneeberger, Kerstin, Tejera, Agueda M, Ayuso, Eduard, Bosch, Fatima, Blasco, Maria A
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2012
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494070/
https://ncbi.nlm.nih.gov/pubmed/22585399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200245
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