Loss of Maternal Annexin A5 Increases the Likelihood of Placental Platelet Thrombosis and Foetal Loss

Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy. We found significant reductions in litter size and foetal w...

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Autors principals: Ueki, Hiroshi, Mizushina, Tomona, Laoharatchatathanin, Titaree, Terashima, Ryota, Nishimura, Yasuhiro, Rieanrakwong, Duangjai, Yonezawa, Tomohiro, Kurusu, Shiro, Hasegawa, Yoshihisa, Brachvogel, Bent, Pöschl, Ernst, Kawaminami, Mitsumori
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494014/
https://ncbi.nlm.nih.gov/pubmed/23145320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00827
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