Loss of Maternal Annexin A5 Increases the Likelihood of Placental Platelet Thrombosis and Foetal Loss

Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy. We found significant reductions in litter size and foetal w...

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Détails bibliographiques
Auteurs principaux: Ueki, Hiroshi, Mizushina, Tomona, Laoharatchatathanin, Titaree, Terashima, Ryota, Nishimura, Yasuhiro, Rieanrakwong, Duangjai, Yonezawa, Tomohiro, Kurusu, Shiro, Hasegawa, Yoshihisa, Brachvogel, Bent, Pöschl, Ernst, Kawaminami, Mitsumori
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494014/
https://ncbi.nlm.nih.gov/pubmed/23145320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00827
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