Loss of Maternal Annexin A5 Increases the Likelihood of Placental Platelet Thrombosis and Foetal Loss

Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy. We found significant reductions in litter size and foetal w...

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Main Authors: Ueki, Hiroshi, Mizushina, Tomona, Laoharatchatathanin, Titaree, Terashima, Ryota, Nishimura, Yasuhiro, Rieanrakwong, Duangjai, Yonezawa, Tomohiro, Kurusu, Shiro, Hasegawa, Yoshihisa, Brachvogel, Bent, Pöschl, Ernst, Kawaminami, Mitsumori
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494014/
https://ncbi.nlm.nih.gov/pubmed/23145320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00827
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