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Bacterial Biosynthetic Gene Clusters Encoding the Anti-cancer Haterumalide Class of Molecules: BIOGENESIS OF THE BROAD SPECTRUM ANTIFUNGAL AND ANTI-OOMYCETE COMPOUND, OOCYDIN A

Haterumalides are halogenated macrolides with strong antitumor properties, making them attractive targets for chemical synthesis. Unfortunately, current synthetic routes to these molecules are inefficient. The potent haterumalide, oocydin A, was previously identified from two plant-associated bacter...

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Detalhes bibliográficos
Main Authors: Matilla, Miguel A., Stöckmann, Henning, Leeper, Finian J., Salmond, George P. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493953/
https://ncbi.nlm.nih.gov/pubmed/23012376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.401026
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