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Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq

Polyketides represent an important class of bioactive natural products with a broad range of biological activities. We identified recently a large trans-acyltransferase (AT) polyketide synthase gene cluster responsible for the biosynthesis of the antifungal, anti-oomycete and antitumor haterumalide,...

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Detalhes bibliográficos
Publicado no:Environ Microbiol
Main Authors: Matilla, Miguel A, Leeper, Finian J, Salmond, George P C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552970/
https://ncbi.nlm.nih.gov/pubmed/25753587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1462-2920.12839
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