Flow-sensitive K(+)-coupled ATP Secretion Modulates Activity of the Epithelial Na(+) Channel in the Distal Nephron

The epithelial Na(+) channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN) is under tonic inhibition by a local purinergic signaling system responding to changes in dietary sodium intake. Normal BK(Ca) channel function is required for flow-sensitive ATP secretion in the ASDN. We tested h...

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Hlavní autoři: Bugaj, Vladislav, Sansom, Steven C., Wen, Donghai, Hatcher, Lori I., Stockand, James D., Mironova, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Membrane Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493900/
https://ncbi.nlm.nih.gov/pubmed/23002235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.408476
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