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Bicarbonate promotes BK-α/β4-mediated K excretion in the renal distal nephron

Ca-activated K channels (BK), which are stimulated by high distal nephron flow, are utilized during high-K conditions to remove excess K. Because BK predominantly reside with BK-β4 in acid/base-transporting intercalated cells (IC), we determined whether BK-β4 knockout mice (β4KO) exhibit deficient K...

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Detalhes bibliográficos
Main Authors: Cornelius, Ryan J., Wen, Donghai, Hatcher, Lori I., Sansom, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532485/
https://ncbi.nlm.nih.gov/pubmed/22993067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00490.2012
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