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Regulation of BK-α expression in the distal nephron by aldosterone and urine pH

In the distal nephron, the large-conductance Ca-activated K (BK) channel, comprised of a pore-forming-α (BK-α) and the BK-β4 subunit, promotes K excretion when mice are maintained on a high-K alkaline diet (HK-alk). We examined whether BK-β4 and the acid-base status regulate apical membrane expressi...

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Detalhes bibliográficos
Main Authors: Wen, Donghai, Cornelius, Ryan J., Yuan, Yang, Sansom, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891257/
https://ncbi.nlm.nih.gov/pubmed/23761673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00171.2013
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