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Blockade of JNK and NFAT Pathways Attenuates Orthopedic Particle-Stimulated Osteoclastogenesis of Human Osteoclast Precursors and Murine Calvarial Osteolysis
Particles released from orthopedic implants attract immune host defense cells to the bone-implant interface and contribute to development of inflammation. The inflammatory microenvironment supports recruitment and differentiation of osteoclasts, the primary culprit of osteolysis. Therefore, understa...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493691/ https://ncbi.nlm.nih.gov/pubmed/22847537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22200 |
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