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Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors()

Development of small molecule drug-like inhibitors blocking both nitric oxide synthase and NFκB could offer a synergistic therapeutic approach in the prevention and treatment of inflammation and cancer. During the course of evaluating the biologic potential of a commercial compound library, 2-phenyl...

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Autores principales: Yu, Xufen, Park, Eun-Jung, Kondratyuk, Tamara P., Pezzuto, John M., Sun, Dianqing
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493622/
https://ncbi.nlm.nih.gov/pubmed/23044819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob26456k
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