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Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors()
Development of small molecule drug-like inhibitors blocking both nitric oxide synthase and NFκB could offer a synergistic therapeutic approach in the prevention and treatment of inflammation and cancer. During the course of evaluating the biologic potential of a commercial compound library, 2-phenyl...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493622/ https://ncbi.nlm.nih.gov/pubmed/23044819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob26456k |
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