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Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by epimuqubilin A via IKK/IκB/NF-κB pathways in lipopolysaccharide-stimulated RAW 264.7 cells

Lipopolysaccharide (LPS)-stimulated RAW 264.7 cells are commonly used as a model for assessing the anti-inflammatory or chemopreventive potential of test compounds. Epimuqubilin A, a norsesterterpene peroxide isolated from marine sponge Latrunculia sp., inhibits nitric oxide production in LPS-stimul...

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Bibliographic Details
Main Authors: Park, Eun-Jung, Cheenpracha, Sarot, Chang, Leng Chee, Pezzuto, John M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237698/
https://ncbi.nlm.nih.gov/pubmed/22180763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phytol.2011.07.009
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